DNLI - デナリ・セラピュ―ティクス (Denali Therapeutics Inc.) デナリ・セラピュ―ティクス

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 DNLIの企業情報

symbol DNLI
会社名 Denali Therapeutics Inc (デナリ・セラピュ―ティクス)
分野(sector) Health Care   ヘルスケア
産業(industry) Biotechnology: Biological Products (No Diagnostic Substances)  
業種 バイオテクノロジ―_メディカルリサ―チ   医療関連(Health Care)
概要 事業概要 デナリ・セラピューティクス(Denali Therapeutics Inc.)はバイオテクノロジー企業である。同社は、アルツハイマー病、パーキンソン病、筋萎縮性側索硬化症(ALS)などの神経変性疾患患者の治療法の発見と開発に従事する。同社は、遺伝的原因及び神経変性疾患の根底にある生物学的プロセスに関する科学的な洞察に基づいて、治療薬の多様なポートフォリオを開発する。同社は、脱遺伝子遺伝子(変異した場合に神経変性疾患を引き起こす遺伝子)、欠陥細胞内輸送、グリア機能障害および軸索変性を含む、神経変性のトリガーまたはエフェクターとして関与する約4つの特異的経路を選択した。同社の開発プログラムには、リソソーム機能経路、グリア細胞生物学的経路、および細胞恒常性経路が含まれる。同社の製品パイプラインには、DNL201、DNL 151、ATV:aSyn、ETV:IDS、DNL747、ATV:TREM2などの薬物候補が含まれる。   デナリ・セラピュ―ティクスは米国のバイオ医薬品会社。アルツハイマ―病、パ―キンソン病、筋萎縮性側索硬化症(ALS)などに代表される神経変性疾患に対する治療薬の発見・開発に従事。疾患の原因やリスク要因に直接対処することを目指し、6つの異なるプログラムで臨床開発及び臨床前開発に取り組む。本社はカリフォルニア州サウス・サンフランシスコ。   Denali Therapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of a portfolio of product candidates for neurodegenerative diseases. Its product pipeline includes LRRK2, RIPK1, TREM2, and Tau. The company was founded by Ryan J. Watts, Marc Tessier-Lavigne, and Alexander Schuth on October 14, 2013 and is headquartered in San Francisco, CA.
本社所在地 151 Oyster Point Blvd. 2nd Floor South San Francisco CA 94080 USA
代表者氏名 Marc Tessier-Lavignec マルクテッシーエ - ラヴィーニェック
代表者役職名 Chairman of the Board Co-Founder
電話番号 +1 650-866-8548
設立年月日 41548
市場名 NASDAQ National Market System
ipoyear 2017年
従業員数 130人
url www.denalitherapeutics.com
nasdaq_url https://www.nasdaq.com/symbol/dnli
adr_tso
EBITDA EBITDA(百万ドル) -124.66400
終値(lastsale) 18.34
時価総額(marketcap) 1738762415.74
時価総額 時価総額(百万ドル) 1690.411
売上高 売上高(百万ドル) 2.28900
企業価値(EV) 企業価値(EV)(百万ドル) 1317.82
当期純利益 当期純利益(百万ドル) -123.13300
決算概要 決算概要 BRIEF: For the six months ended 30 June 2018 Denali Therapeutics Inc revenues increased from $0K to $2.3M. Net loss increased 80% to $78.4M. Revenues reflect an increase in demand for the Company's products and services due to favorable market conditions. Higher net loss reflects Research_Development Expense - Balanci increase of 89% to $68.7M (expense) Stock-based Compensation in R&D increase from $1.2M to $4.3M (expense) Selling.

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 DNLIのニュース

   Biogen reports 11.16% passive stake in Denali Therapeutics (NASDAQ:DNLI)  2020/09/28 20:37:54 Seeking Alpha
Biogen purchases ~13.3M shares of Denali Therapeutics (NASDAQ:DNLI) on September 22. This represents 11.16% of total shares outstanding. The stake does not
   The Daily Biotech Pulse: Moderna Inks 2 R&D Deals, BioNTech To Buy Manufacturing Facility, Dyne Therapeutics IPO  2020/09/17 11:59:47 Benzinga
Here's a roundup of top developments in the biotech space over the last 24 hours: Scaling The Peaks (Biotech Stocks Hitting 52-week Highs Sept. 16) Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) (the first subject has been dosed in a Phase 3 trial evaluating etrasimod for the potential treatment of moderately to severely active ulcerative colitis) Beigene Ltd (NASDAQ: BGNE ) BioLife Solutions Inc (NASDAQ: BLFS ) Checkpoint Therapeutics Inc (NASDAQ: CKPT ) Denali Therapeutics Inc (NASDAQ: DNLI ) Dr.Reddy's Laboratories Ltd (NYSE: RDY ) (announced a deal with Russia for 100 million doses of Sputnik-V vaccine against the coronavirus) Fortress Biotech (NASDAQ: FBIO ) Guardant Health Inc (NASDAQ: GH ) Immunovant Inc (NASDAQ: IMVT ) Insmed Incorporated (NASDAQ: INSM ) InVitae Corp (NYSE: NVTA ) Marinus Pharmaceuticals Inc (NASDAQ: MRNS ) Mersana Therapeutics Inc (NASDAQ: MRSN ) Mirati Therapeutics Inc (NASDAQ: MRTX ) Myokardia Inc (NASDAQ: MYOK ) Nevro Corp (NYSE: NVRO ) Novocure Ltd (NASDAQ: NVCR ) Pacific Biosciences of California Inc (NASDAQ: PACB ) Protagonist Therapeutics Inc (NASDAQ: PTGX ) RedHill Biopharma Ltd (NASDAQ: RDHL ) Revance Therapeutics Inc (NASDAQ: RVNC ) SI-Bone Inc (NASDAQ: SIBN ) Silk Road Medical Inc (NASDAQ: SILK ) Turning Point Therapeutics Inc (NASDAQ: TPTX ) Down In The Dumps (Biotech Stocks Hitting 52-week Lows Sept. 16) PainReform Ltd (NASDAQ: PRFX ) Pandion Therapeutics Inc (NASDAQ: PAND ) SILENCE THERAPE/S ADR (NASDAQ: SLN ) Stocks In Focus Moderna Announces 2 R&D Collaborations For Up To $880M Moderna Inc (NASDAQ: MRNA ) and Vertex Pharmaceuticals Incorporated (NASDAQ: VRTX ) announced a three-year strategic research collaboration and licensing agreement aimed at the discovery and development of lipid nanoparticles and mRNAs for the delivery of gene-editing therapies for cystic fibrosis.
   The Daily Biotech Pulse: Moderna Expands Into Switzerland, Tiziana To Spin Off Testing Unit, Metacrine IPO  2020/09/16 12:00:28 Benzinga
Scaling The Peaks (Biotech Stocks Hitting 52-week Highs Sept. 15) Avidity Biosciences Inc (NASDAQ: RNA ) Beigene Ltd (NASDAQ: BGNE ) Bicycle Therapeutics PLC (NASDAQ: BCYC ) BioLife Solutions Inc (NASDAQ: BLFS ) Checkpoint Therapeutics Inc (NASDAQ: CKPT ) Denali Therapeutics Inc (NASDAQ: DNLI ) Fate Therapeutics Inc (NASDAQ: FATE ) Guardant Health Inc (NASDAQ: GH ) Horizon Therapeutics PLC (NASDAQ: HZNP ) Immunovant Inc (NASDAQ: IMVT ) InVitae Corp (NYSE: NVTA ) Jounce Therapeutics Inc (NASDAQ: JNCE ) Marinus Pharmaceuticals Inc (NASDAQ: MRNS ) ( announced a positive late-stage readout for ganaxolone) Mirati Therapeutics Inc (NASDAQ: MRTX ) Momenta Pharmaceuticals, Inc. (NASDAQ: MNTA ) Myokardia Inc (NASDAQ: MYOK ) Novocure Ltd (NASDAQ: NVCR ) Outset Medical Inc (NASDAQ: OM ) (more than doubled on its Wall Street debut) Repare Therapeutics Inc (NASDAQ: RPTX ) Revance Therapeutics Inc (NASDAQ: RVNC ) Shockwave Medical Inc (NASDAQ: SWAV ) SI-Bone Inc (NASDAQ: SIBN ) Silk Road Medical Inc (NASDAQ: SILK ) TRACON Pharmaceuticals Inc (NASDAQ: TCON ) Down In The Dumps (Biotech Stocks Hitting 52-week Lows Sept. 15) Histogen Inc (NASDAQ: HSTO ) PainReform Ltd (NASDAQ: PRFX ) Satsuma Pharmaceuticals Inc (NASDAQ: STSA ) SILENCE THERAPE/S ADR (NASDAQ: SLN ) Stocks In Focus Roche Gets Label Expansion For Cancer Screening Test Roche Holdings AG Basel (OTC: RHHBY ) announced FDA approval for the expanded use of CINtec PLUS Cytology, its first triage test based on biomarker technology for women whose cervical cancer screening results are positive for high-risk types of human papillomavirus.
   The Daily Biotech Pulse: Marinus Epilepsy Study Meets Goal, Novavax Reaches Vaccine Manufacturing Deal, Outset Medical's IPO  2020/09/15 11:55:39 Benzinga
Scaling The Peaks (Biotech Stocks Hitting 52-week Highs Sept. 14) 10X Genomics Inc (NASDAQ: TXG ) Applied Molecular Transport Inc. (NASDAQ: AMTI ) Avenue Therapeutics Inc (NASDAQ: ATXI ) Avidity Biosciences Inc (NASDAQ: RNA ) BioLife Solutions Inc (NASDAQ: BLFS ) Denali Therapeutics Inc (NASDAQ: DNLI ) Guardant Health Inc (NASDAQ: GH ) Immunomedics, Inc. (NASDAQ: IMMU ) - announced a deal to be bought by Gilead Sciences, Inc. (NASDAQ: GILD ) for $21 billion Inspire Medical Systems Inc (NYSE: INSP ) Kintara Therapeutics Inc (NASDAQ: KTRA ) Kura Oncology Inc (NASDAQ: KURA ) Nurix Therapeutics Inc (NASDAQ: NRIX ) Pacific Biosciences of California Inc (NASDAQ: PACB ) (announced the appointment of Susan Kim as CFO, effective Sept. 28) Shockwave Medical Inc (NASDAQ: SWAV ) SI-Bone Inc (NASDAQ: SIBN ) Silk Road Medical Inc (NASDAQ: SILK ) Stoke Therapeutics Inc (NASDAQ: STOK ) Trillium Therapeutics Inc (NASDAQ: TRIL ) Turning Point Therapeutics Inc (NASDAQ: TPTX ) Down In The Dumps (Biotech Stocks Hitting 52-week Lows Sept. 14) Acorda Therapeutics Inc (NASDAQ: ACOR ) AEterna Zentaris Inc. (NASDAQ: AEZS ) BELLUS Health Inc (NASDAQ: BLU ) PainReform Ltd (NASDAQ: PRFX ) Predictive Oncology Inc (NASDAQ: POAI ) Sunesis Pharmaceuticals, Inc. (NASDAQ: SNSS ) Stocks In Focus Marinus Reports Positive Late-Stage Readout In Epilepsy Marinus Pharmaceuticals Inc (NASDAQ: MRNS ) announced positive top-line results from its registrational Phase 3 clinical trial, dubbed Marigold, evaluating the use of oral ganaxolone in children and young adults with CDKL5 deficiency disorder, a rare, genetic epilepsy with refractory seizures.
   MedGenome announces Strategic Collaboration in Parkinson's Disease with Denali Therapeutics  2020/08/26 09:00:00 PR Newswire
FOSTER CITY, California, Aug. 26, 2020 /PRNewswire/ -- MedGenome, a leading genomic diagnostics, research and data company based in Foster City, CA and Bangalore, India, today announced that it has formed a strategic discovery collaboration focused on novel discoveries in Parkinson's…
   Denali Therapeutics Reports Second Quarter 2020 Financial Results and Business Highlights  2020/08/07 16:30:00 Benzinga
SOUTH SAN FRANCISCO, Calif., Aug. 07, 2020 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (NASDAQ:DNLI), a biopharmaceutical company developing a broad …
   The Daily Biotech Pulse: Novavax Vaccine Deals, Trevena Awaits FDA Decision, 2 IPOs  2020/08/07 11:34:07 Benzinga
Scaling The Peaks (Biotech Stocks Hitting 52-week Highs Aug. 6) ADiTx Therapeutics Inc (NASDAQ: ADTX ) (announced introduction of AditxtScore for COVID-19 to be used in detecting antibodies against SARS-CoV-2 antigens) Axonics Modulation Technologies Inc (NASDAQ: AXNX ) Biocept Inc (NASDAQ: BIOC ) (announced an agreement with Aegea for a highly sensitive PCR-based assay designed by the latter for detecting the COVID-19 virus) DarioHealth Corp (NASDAQ: DRIO ) Denali Therapeutics Inc (NASDAQ: DNLI )( announced selection of candidate to enter Phase 3 study in Parkinson's disease) Editas Medicine Inc (NASDAQ: EDIT )(moved on M&A speculation) Emergent Biosolutions Inc (NYSE: EBS ) Halozyme Therapeutics, Inc. (NASDAQ: HALO ) Harvard Bioscience, Inc. (NASDAQ: HBIO ) ITAMAR MED LTD/S ADR (NASDAQ: ITMR ) Meridian Bioscience, Inc. (NASDAQ: VIVO ) Natera Inc (NASDAQ: NTRA ) PDL BioPharma Inc (NASDAQ: PDLI ) Sangamo Therapeutics Inc (NASDAQ: SGMO ) (reacted to its second-quarter results) Shockwave Medical Inc (NASDAQ: SWAV ) SurModics, Inc. (NASDAQ: SRDX )(reacted to its second-quarter results) Twist Bioscience Corp (NASDAQ: TWST ) Unity Biotechnology Inc (NASDAQ: UBX ) Zoetis Inc (NYSE: ZTS ) (reacted to its second-quarter results) Down In The Dumps (Biotech Stocks Hitting 52-week Lows Aug. 6) Nkarta Inc (NASDAQ: NKTX ) Orchard Therapeutics PLC – ADR (NASDAQ: ORTX )(announced its second-quarter results) Stocks In Focus Zosano Clinches Distribution Deal For Investigational Migraine Patch Zosano Pharma Corp (NASDAQ: ZSAN ) said it has partnered with Eversana commercialize and distribute Qtrypta in the U.S.
   Mid-Afternoon Market Update: Dow Jumps Over 100 Points; Denali Therapeutics Shares Spike Higher  2020/08/06 14:36:00 Benzinga
Toward the end of trading Thursday, the Dow traded up 0.42% to 27316.16 while the NASDAQ rose 0.69% to 11074.09. The S&P also rose, gaining 0.42% to …
   Why Shares of Denali Therapeutics Are Skyrocketing  2020/08/06 13:54:20 Benzinga
Shares of Denali Therapeutics Inc (NASDAQ: Full story available on Benzinga.com
   Denali Therapeutics Announces Phase 1b Study by Partner Sanofi of RIPK1-Inhibitor DNL758 (SAR443122) in COVID-19 Patients  2020/07/29 13:00:00 GlobeNewswire
Dosing of DNL758 (SAR443122) has commenced in a randomized, double-blind, placebo-controlled Phase 1b trial to evaluate safety and effect on the immune…
   Denali Therapeutics Provides Broad Update on Its RIPK1 Program Partnered With Sanofi  2020/06/09 20:30:00 GlobeNewswire
Denali and Sanofi pause DNL747(a) clinical activities based on the totality of DNL747 data and a superior profile of backup compound DNL788(b)Denali and…
   What Makes Denali Therapeutics Inc. (DNLI) a New Buy Stock  2020/05/21 16:00:14 Zacks Investment Research
Denali Therapeutics Inc. (DNLI) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy).
   Denali Therapeutics Reports First Quarter 2020 Financial Results and Provides COVID-19 Response Update  2020/05/07 20:30:00 GlobeNewswire
SOUTH SAN FRANCISCO, May 07, 2020 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (NASDAQ: DNLI), a biopharmaceutical company developing a broad portfolio…
   The Daily Biotech Pulse: Roche Obtains FDA Emergency Use Authorization For COVID-19 Test, Chembio Appoints New CEO, Inovio Slumps On Earnings  2020/03/13 11:52:53 Benzinga
Here's a roundup of top developments in the biotech space over the last 24 hours: Scaling The Peaks (Biotech stocks that hit 52-week highs March 12.) Masimo Corporation (NASDAQ: MASI ) Down In The Dumps (Biotech stocks that hit 52-week lows March 12.) Abbott Laboratories (NYSE: ABT ) ABIOMED, Inc. (NASDAQ: ABMD ) Acasti Pharma Inc (NASDAQ: ACST ) Accelerate Diagnostics Inc (NASDAQ: AXDX ) AcelRx Pharmaceuticals Inc (NASDAQ: ACRX ) Achieve Life Sciences Inc (NASDAQ: ACHV ) Acorda Therapeutics Inc (NASDAQ: ACOR ) Adamas Pharmaceuticals Inc (NASDAQ: ADMS ) Adamis Pharmaceuticals Corp (NASDAQ: ADM ) Adaptive Biotechnologies Corp (NASDAQ: ADPT ) ADDEX THERAPEUT/ADR (NASDAQ: ADXN ) ADMA Biologics Inc (NASDAQ: ADMA ) Aeglea Bio Therapeutics Inc (NASDAQ: AGLE ) Aerie Pharmaceuticals Inc (NASDAQ: AERI ) AEterna Zentaris Inc. (NASDAQ: AEZS ) Affimed NV (NASDAQ: AFMD ) Aileron Therapeutics Inc (NASDAQ: ALRN ) Aimmune Therapeutics Inc (NASDAQ: AIMT ) Akari Therapeutics PLC (NASDAQ: AKTX ) Akcea Therapeutics Inc (NASDAQ: AKCA ) Akero Therapeutics Inc (NASDAQ: AKRO ) Akers Biosciences Inc (NASDAQ: AKER ) Akorn, Inc.
   Has Denali Therapeutics (DNLI) Outpaced Other Medical Stocks This Year?  2020/02/07 16:30:10 Zacks Investment Research
Is (DNLI) Outperforming Other Medical Stocks This Year?

 関連キーワード  (バイオテクノロジ―_メディカルリサ―チ 米国株 デナリ・セラピュ―ティクス DNLI Denali Therapeutics Inc.)

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